‘Vitamin E in dermatology’. Thank you again. ‘Cosmeceuticals vitamins’. ‘Intrinsic and extrinsic factors in skin ageing: a review’. Dhaval Bhanusali, MD, a dermatologist in NYC, adds it to patients’ routines because “it’s a great anti-inflammatory that can help adjust the irritation of many strong topicals.” And it matches well with salicylic acid because “they both work toward the same end goal of treating pigmentation and evening skin tone,” says Tiffany Libby, MD, a fellow NYC derm. One study found that a topical combination of vitamin C and a centella asiatica extract significantly improved skin suppleness, firmness, and hydration, as well as improving the appearance of wrinkles, after 6 weeks of use [36]. Lowe, N. (2006). ‘Practical uses of botanicals in skin care’. There’s no third wheel here! In fact, a large randomized controlled study found that the combination of niacinamide and NAG worked really well at reducing pigmentation. Niacinamide, which is also called nicotinamide, is one of two major forms of vitamin B3 (niacin) found in supplements (the other is nicotinic acid). & Brody, N. (2011). Kornhauser, A., Coelho, S. & Hearing, V. (2010). Specifically, 4% niacinamide combined with 2% NAG was significantly more effective at reducing pigmentation than a vehicle control formulation [64]. ‘Evaluation of topical formulations of aqueous extract of Centella asiatica on open wounds in rats’. We have already seen earlier how vitamin C and glycolic acid enhanced each others collagen-boosting effects when combined with centella asiatica. Glycolic acid, alone, boosted collagen production 2-fold (2x), 3-fold (3x) when combined with centella asiatica, and four-fold (4x) when combined with both vitamin C, Centella Asiatica + Vitamin A + Vitamin C + Vitamin E = 3x, Centella Asiatica + Vitamin C + Glycolic Acid = 4x, Zinc oxide is a mineral (physical/inorganic) sunscreen, which means that it protects the skin from UVA and UVB radiation by reflecting and scattering light. AHAs, such as glycolic and lactic acid, act as chemical exfoliants and help remove dead skin cells and loosen the top layer of skin. (2013). ‘Optimization of physiological lipid mixtures for barrier repair’. Poli, F., Ribet, V., Lauze, C., Adhoute, H. & Morinet, P. (2005). I recommend you put on benzoyl peroxide in the morning and use salicylic acid and retinoids at night. Then apply niacinamide to regulates your sebum and minimizes pores. Photochem. ‘Topical vitamin C and the skin: mechanisms of action and clinical applications’. Great for acne breakouts, salicylic acid shrinks them up, and fast. ‘The effect of Centella asiatica, vitamins, glycolic acid and their mixtures preparations in stimulating collagen and fibronectin synthesis in cultured human skin fibroblast’. Ceramides account for about 45-50% of this mixture, cholesterol for approximately 25%, and free fatty acids for around 10-15%, When this lipid matrix is depleted, skin can become dehydrated. However, these ingredients can be found in OTC moisturizers and, when applied to the skin, replenish the substances that the stratum corneum is lacking, thus improving skin hydration [28]. Posted 12:27 am by & filed under .-sunscreen With antioxidants like vitamin C and E working in tandem to undo the damage caused by UV rays, you’re probably thinking how it makes ‘RALGA (Diacneal), a retinaldehyde and glycolic acid association and post-inflammatory hyperpigmentation in acne – a review’. & Lupo, M. (2009). In fact, the anti-aging effects of vitamin C are enhanced even further when it is combined with, Timeless Skincare 20% Vitamin C, E, & Ferulic Acid Serum, SeoulCeuticals Day Glow Serum 20% Vitamin C, E, & Ferulic Acid Serum With Hyaluronic Acid. Lactic acid is a type of alpha hydroxy acid(AHA) while Salicylic acid is a type of beta-hydroxy acid(BHA). I was so confused. Gehring, W. (2004). For this reason, antioxidants and sunscreens make a perfect pairing and are much more effective when used together. “Vitamin E makes vitamin C four times stronger.” Wow! Also to know i can mix Gycolic Acid with Vitamin C. Yeah! A number of studies that have investigated the wound-healing benefits of centella asiatica have found that topical application of the extract increases the production of collagen [34]. ‘Comparison of topical therapy for striae alba (20% glycolic acid/ 0.05% tretinoin versus 20% glycolic acid/ 10% L-ascorbic acid)’. & Gajjar, A. Can you tell i love Vit C? Resveratrol + Glycolic Acid = Reduced Hyperpigmentation. This is all down to the molecular structure of each ingredient." Related Reading: Niacinamide & Retinol Together = A Perfect Pair! TruSkin Vitamin C-Plus Super Serum. Siu, S., Ferzili, G. & Brody, N. (2017). This is because both vitamin C and glycolic acid are known to boost collagen levels in the skin and it appears that their effects may be additive. As you can see, niacinamide and salicylic acid offer similar benefits but work in slightly different ways. Products That Combine Ceramides & Cholesterol & Fatty Acids: Centella asiatica is a tropical medicinal plant native to Southeast Asia that has antioxidant, anti-aging, and wound healing properties. Recommended Reading: Can You Use Glycolic Acid and Retinol Together? Another great skincare ingredient combination for hyperpigmentation and melasma is glycolic acid and resveratrol. vitamin B3) comes in. Niacinamide is able to stabilise the skins barrier function by reducing the amount of water lost and improving hydration [51]. However, initially, retinol can cause irritation and dryness of the skin by damaging the skins barrier and increasing transepidermal water loss (TEWL) [50]. I like how my skin looks after using for a few days! Read More. Man, M., Feingold, K. & Elias, P. (1993). Vitamin C and glycolic acid are also useful for treating hyperpigmentation as both are effective at inhibiting tyrosinase and decreasing melanin production [53][45]. Multitasking azelaic and salicylic acids mixed with soothing ingredients steadily targets tenacious post-breakout marks, clarifies skin and reduces the look of redness. “It’s essential for collagen production, which gives our skin support and structure to combat fine lines and wrinkles,” Dr. Libby says. Green Tea + Caffeine = Increased Protection Against UVB-induced Skin Cancer. 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